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Symbol Name ID |
Kmt2d
lysine (K)-specific methyltransferase 2D MGI:2682319 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Human Phenotypes | Autoimmune thrombocytopenia |
Recurrent otitis media |
Abnormality of immune system physiology |
Recurrent aspiration pneumonia |
Recurrent infections |
| Disease(s) Associated with KMT2D | |||||
| Kabuki syndrome |
| Mouse Phenotypes | immune system phenotype |
increased B cell proliferation |
abnormal B cell differentiation |
increased germinal center B cell number |
decreased mature B cell number |
decreased follicular B cell number |
decreased B cell number |
increased spleen germinal center number |
increased spleen germinal center size |
decreased IgG1 level |
decreased IgM level |
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| Availability | Mouse Genotype | |||||||||||
| Kmt2dtm1.1Kaig/Kmt2dtm1.1Kaig Cd19tm1(cre)Cgn/Cd19+ (conditional) |
* | |||||||||||
| Kmt2dtm1.1Kaig/Kmt2dtm1.1Kaig Ighg1tm1(cre)Cgn/Ighg1+ (conditional) |
* | |||||||||||
| Kmt2dtm1.1Kaig/Kmt2d+ Cd19tm1(cre)Cgn/Cd19+ (conditional) |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/30/2024 MGI 6.23 |
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